| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 19-09-25 19:00 | Sparta Roterdão | FC Twente Enschede | 1:5 |
| 20-09-25 15:30 | FC Volendam | Excelsior Roterdão | 1:2 |
| 20-09-25 17:45 | FC Groningen | Telstar | 2:0 |
| 20-09-25 19:00 | Fortuna Sittard | FC Utrecht | 1:0 |
| 20-09-25 20:00 | NAC Breda | Heracles Almelo | 2:1 |
| 21-09-25 11:15 | PEC Zwolle | Go Ahead Eagles Deventer | 0:2 |
| 21-09-25 13:30 | PSV Eindhoven | Ajax Amsterdão | 2:2 |
| 21-09-25 13:30 | SC Heerenveen | NEC Nijmwegen | 3:2 |
| 21-09-25 15:45 | AZ Alkmaar | Feyenoord Rotterdão | 3:3 |